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pan-European project decoding the DNA

Of all the opportunities offered by the decoding of the human genome, one of the most exciting is the chance to learn how DNA determines health. Thanks to a European research project, this medical breakthrough is getting a little closer to reality. The project, NanoDNAsequencing, discovered a novel method to decode human DNA, paving the way for personalised therapy based on an individual’s genetic profile.


for fast DNA sequencing

One of the great scientific and technological problems of today is understanding the structure and function of DNA and closely related development of inexpensive methods for DNA sequencing. The latter promises to revolutionize both our understanding of DNA as well as significantly advance personalized medicine...
Other areas: Photovoltaics; Quantum-mechanical disordered and chaotic systems; Quasicrystals; High-performance scientific programming.
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Dna translocations

Determination of genetic code embedded in DNA molecules is fundamental to molecular biology and medicine. Alternative, fast and low-cost methods for DNA sequencing are in high demand. We report on DNA translocations experiments through the solid state nanopores, a technique that has potential to meet those demands. We measured translocation of λ-DNA through 5 and 10 nm silicon nitride nanopores...
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Time-dependent non-equilibrium transport
through molecule in nonorthogonal basis set

Microscopic theory of non-equilibrium electronic transport under time-dependent bias through the molecule (or quantum dot) embedded between two semi-infinite metallic electrodes is developed in the non-orthogonal single-particle basis set using ab-initio formalism of Greens functions. The equilibrium zeroth order electron Green’s function and self-energy are corrected by the corresponding time- inhomogeneous dynamical contributions, derived in Hartree approximation in steady-state linear-response regime. It was shown that nonorthogonality contributes to these dynamical contributions by introducing terms related to the central region-electrode  interface, appearing only in time-dependent case. The expression for current is also derived, where nonorthogonal-induced dynamical correction give an additional current, not present in the orthogonal description. It is shown that the obtained expression for current is gauge-invariant and demonstrated that the omission of the additional current violates charge conservation. It is also shown that the additional current term vanishes in orthogonal case.
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Interaction of UV light with amorphous small-molecule organic thin films

We study interaction of thin films of small-molecule organic blue-emitter materials, such as N,N′-bis(3-methylphenyl)-N,N′-bis(phenyl)benzidine (TPD) and 4,4′-bis(2,2-diphenylvinyl)-1,1′-biphenyl (DPVBi), with UV light. Films are stable in vacuum, but readily degrade in the presence of oxygen. Thus, the necessary condition for interaction (degradation) is the simultaneous presence of UV light and oxygen. These impurities are responsible for increased morphological stability of irradiated films and quenching of photoluminescence (PL).
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Electrical transport and magnetotransport properties of cuprates

The work in this field of research is being done as a part of long-lasting collaboration with solid state physics laboratory in Orsay, LPS (Laboratoire de Physique des Solides, Universite Paris-Sud, Orsay, France) and especially with dr Helene Raffy. Experiments were conducted in LPS (dr H. Raffy, dr Z.Z. Li, dr L. Fruchter and dr F. Bouquet) and also in NHMFL in Grenoble, with the help of dr P. Monceau and dr G. Reményi. 
Other areas: Organic quasi-2D superconductors
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Micro-rods of oxidized pentacene

Pentacene is material widely. Pentacene is hole-type semiconductor used in organic electronic devices, well-known for its high charge carrier mobility as high as 35 cm2V-1s-1 at room temperature. Performance of devices made from organic thin films strongly depends on their morphology and it is often limited by the presence of molecular disorder and grain boundaries, which reduce mobility of charge carriers of a material.
To improve charge transport properties thermal annealing could be used. Prolonged annealing of pentacene films leads to surprising result: nano- and micro-scale rod-shaped structures are forming on film surface. Based on scanning electron microscopy measurements, it is supposed that these structures are crystalline. Their UV-vis absorbance indicates that they are composed of more than one species of oxidized pentacene molecules, including 6,13-pentacenequinone.

Images of crystal-like structures (micro-rods and micro-crystals) formed on the surface of pentacene films obtained by a), d) optical and b), c) scanning electron microscopes.
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